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Open-weight model

helico-masked-contact-exp22

by Tim O'Donnell timodonnell/helico-masked-contact-exp22

helico-masked-contact-exp22 is an open-weight model from Tim O'Donnell. Its published files total 3.0 GB.

Full-size 368.5M-parameter Helico initialized from Protenix basedefaultv1.0.0, fine-tuned for 20,000 optimizer updates and 640,000 weighted crop draws on the pinned Protenix-v1 PDB split.

Parameters—
Context—
Weights3.0 GB
License—
AccessOpen weights
Monthly Downloads—

Model Card

Full-size 368.5M-parameter Helico initialized from Protenix basedefaultv1.0.0, fine-tuned for 20,000 optimizer updates and 640,000 weighted crop draws on the pinned Protenix-v1 PDB split. This release contains regular and exponential-moving-average weights; optimizer state remains in the durable training archive. The model preserves MSA input and adds three-state unknown/no-contact/contact pair conditioning plus a symmetric contact-prediction head. Contacts use minimum token heavy-atom distance <5 Å with conservative observed-atom validity. Absorbing corruption is value-independent, with endpoint/sparse-mask oversampling and 20% MSA dropout. Coordinate diffusion and distogram parameters are…

Excerpt from the card by Tim O'Donnell.

Identity and Version

Repository
timodonnell/helico-masked-contact-exp22
Publisher
Tim O'Donnell
Task
Not stated by the source
Modality
Other
Library
Not stated by the source
Parameters
Not stated by the source
Languages
Not stated by the source
Revision
ea1f0c7bd72ba169c09ff1e9757578a089023a5d
First published
2026-10-15
Last updated
2026-10-16

Files and Weights

7 files, 3.0 GB in total. The weights are 2 files totalling 3.0 GB in pt.

Weights2 files · 3.0 GB
Configuration1 file · 19.7 KB
Documentation1 file · 5.7 KB
Other2 files · 146 B
Repository1 file · 1.5 KB
Every file
FileTypeSizeSHA-256
ema.ptWeights1.5 GB 64cf2d396bfc
raw.ptWeights1.5 GB 8e1b8caaa7d1
data.lock.jsonConfiguration19.7 KB —
README.mdDocumentation5.7 KB —
ema.sha256Other73 B —
raw.sha256Other73 B —
.gitattributesRepository1.5 KB —

License and Download

License
Not stated by the source
Access
Open weights, no gate
Download size
3.0 GB
Download from Tim O'Donnell

Released by Tim O'Donnell through its official repository on Hugging Face.

Built From

  • Trained on (disclosed) timodonnell/helico-protenix-v1-pdb

Memory Requirements

PrecisionWeights in memory
As published3.0 GB

Weights only, from the published parameter count; the key-value cache and runtime add to this.