Model weights for InstructPro2: Natural Language and Biological Grounding Guided De Novo Protein Design — a 3.2B protein design model that generates sequences from natural-language function descriptions, optionally conditioned on a ligand or an antigen. The Stage 2 checkpoints are larger because they carry the gated cross-attention adapters and the frozen ChemBERTa and ESM-2 encoders. Pass a checkpoint to the scripts in the code repository: The scripts set the architecture mode and the generation settings for each checkpoint; see the code repository's README.
Independent publisher
Charles Novak
charlesnovak
Models in Library1
Datasets in Library0
Models on Hugging Face2
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