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Open-weight model · Text generation

sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext

by WangLab UofT wanglab/sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext

sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext is a model for text generation from WangLab UofT, released under other (access requested at publisher). It has 9.4B parameters. At 16-bit it needs about 22.6 GB of GPU memory, which fits on 1x MI300X from $1.85 an hour, at the lowest prices in the SAVRN Index.

Qwen3.5-9B fine-tuned to reason mechanistically about genetic (CRISPR) perturbations and predict how a queried pathway responds — upregulated, downregulated, or unchanged — in a given cell.

Parameters9.4B
Context—
Weights18.9 GB
Licenseother
AccessAccess requested at publisher
Monthly Downloads—

Runs On

What it takes to serve sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext (9.4B parameters): the memory its weights need at each precision, and the cheapest way to rent enough data-center GPUs to hold them.

PrecisionWeightsMemory neededCheapest setupPer hourAlso fits
16-bit 18.8 GB 22.6 GB 1x MI300X (192 GB)
Vultr
$1.85 1x H100 $1.99 · 1x MI325X $2.00
8-bit 9.4 GB 11.3 GB 1x MI300X (192 GB)
Vultr
$1.85 1x H100 $1.99 · 1x MI325X $2.00
4-bit 4.7 GB 5.6 GB 1x MI300X (192 GB)
Vultr
$1.85 1x H100 $1.99 · 1x MI325X $2.00

Memory is the weights at that precision plus 20% for the runtime and a short context; a long context needs more. Prices are the lowest on-demand hourly rates in the SAVRN Index, read Oct 18, 2026.

sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext on every accelerator the SAVRN Index prices, at every precision

Model Card

Qwen3.5-9B fine-tuned to reason mechanistically about genetic (CRISPR) perturbations and predict how a queried pathway responds — upregulated, downregulated, or unchanged — in a given cell. This is the cell-text arm of BioReasonCell: the v9.9 SFT recipe, with one change. The model gets no STATE cell embedding. It reads the cell as text instead, a Cell Context: block in the prompt, so it is a plain text model and every input it needs can be built from a new screen's h5ad. The block follows the queried pathway, and the prompt's opening reads "Given a cell's context, a genetic perturbation, …": Top Expressed Genes are the 50 most abundant genes of the line's non-targeting control cells…

Excerpt from the card by WangLab UofT, licensed other.

Identity and Version

Repository
wanglab/sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext
Publisher
WangLab UofT
Task
Text generation
Modality
Text
Library
transformers
Parameters
9.4B parameters
Languages
Not stated by the source
Revision
5513926f8cc693bb2679d07e47a3bd07c7004ebf
First published
2026-10-15
Last updated
2026-10-16

Files and Weights

9 files, 18.9 GB in total. The weights are 2 files totalling 18.9 GB in pt, safetensors.

Weights2 files · 18.9 GB
Configuration2 files · 2.9 KB
Tokenizer2 files · 20.0 MB
Documentation1 file · 8.6 KB
Other1 file · 7.8 KB
Repository1 file · 1.6 KB
Every file
FileTypeSizeSHA-256
cell_projection.ptWeights100.9 MB —
model.safetensorsWeights18.8 GB —
config.jsonConfiguration2.8 KB —
generation_config.jsonConfiguration141 B —
README.mdDocumentation8.6 KB —
chat_template.jinjaOther7.8 KB —
.gitattributesRepository1.6 KB —
tokenizer.jsonTokenizer20.0 MB —
tokenizer_config.jsonTokenizer7.5 KB —

License and Download

License
other
Access
Access requested at publisher
Download size
18.9 GB
Request access from WangLab UofT

WangLab UofT grants access through its official repository on Hugging Face.

Built From

Memory Requirements

PrecisionWeights in memory
As published18.9 GB
16-bit18.8 GB
8-bit9.4 GB
4-bit4.7 GB

Weights only, from the published parameter count; the key-value cache and runtime add to this.

Questions About sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext

How much GPU memory does sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext need?

About 22.6 GB at 16-bit and 5.6 GB at 4-bit: the weights (9.4B parameters) plus a working margin. A long context needs more.

What is the cheapest GPU to run sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext on?

At 16-bit, 1x MI300X from $1.85 an hour; at 4-bit, 1x MI300X from $1.85 an hour, at the lowest on-demand prices the SAVRN Index lists.

What license is sft_gene_pathway_v9_9_100k_a256bs32_9b_celltext released under?

other, as its publisher declares it. Read the license text before commercial use.

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